A Fusion DNA Vaccine Encoding Middle Version of HBV Envelope Protein Fused to Interleukin-21 Did Not Enhance HBV-Specific Immune Response in Mice

DNA vaccination can generate both humoral and cellular immunity, resulting in potential prophylactic and therapeutic vaccines in variety of conditions, including hepatitis B virus (HBV) infection. Fusion of cytokine gene is one of the ways to increase the immunogenicity of DNA vaccine. Interleukin (...

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Detalles Bibliográficos
Main Authors: Zhang, Ye, Su, Wen-Jing, Wang, Jue, Bai, Xue-Fan, Huang, Chang-Xing, Lian, Jian-Qi
Formato: Artigo
Idioma:Inglês
Publicado: Mary Ann Liebert, Inc. 2014
Assuntos:
Original Reports
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4216998/
https://ncbi.nlm.nih.gov/pubmed/25211639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/vim.2014.0051
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