ELK4 neutralization sensitizes glioblastoma to apoptosis through downregulation of the anti-apoptotic protein Mcl-1

Glioma is the most common adult primary brain tumor. Its most malignant form, glioblastoma multiforme (GBM), is almost invariably fatal, due in part to the intrinsic resistance of GBM to radiation- and chemotherapy-induced apoptosis. We analyzed B-cell leukemia–2 (Bcl-2) anti-apoptotic proteins in G...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Day, Bryan W., Stringer, Brett W., Spanevello, Mark D., Charmsaz, Sara, Jamieson, Paul R., Ensbey, Kathleen S., Carter, Jacinta C., Cox, Joanne M., Ellis, Vicky J., Brown, Christopher L., Walker, David G., Inglis, Po L., Allan, Suzanne, Reynolds, Brent A., Lickliter, Jason D., Boyd, Andrew W.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Oxford University Press 2011
विषय:
Basic and Translational Investigations
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3199151/
https://ncbi.nlm.nih.gov/pubmed/21846680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nor119
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