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Relationship between phosphorylation and activity of heme-regulated eukaryotic initiation factor 2 alpha kinase.

In heme-deficient reticulocytes and their lysates, a heme-regulated inhibitor of protein synthesis is activated; this inhibitor is a cyclic AMP-independent protein kinase that specifically phosphorylates the alpha subunit of the eukaryotic initiation factor 2 (eIF-2 alpha). Heme regulates this kinas...

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Détails bibliographiques
Auteurs principaux: Fagard, R, London, I M
Format: Artigo
Langue:Inglês
Publié: 1981
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC319904/
https://ncbi.nlm.nih.gov/pubmed/6940153
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