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A PLACEBO CONTROLLED TRIAL OF MEMANTINE AS AN ADJUNCT TO ORAL NALTREXONE FOR OPIOID DEPENDENCE
BACKGROUND: Preclinical findings suggest that the inhibition of NMDA glutamatergic neurotransmission may have beneficial effects in the treatment of opioid dependence. AIMS: We hypothesized that memantine, a low-potency, uncompetitive NMDA receptor antagonist, would be safe and effective when used a...
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| Asıl Yazarlar: | , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2011
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3199033/ https://ncbi.nlm.nih.gov/pubmed/21715107 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drugalcdep.2011.05.019 |
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