A PLACEBO-CONTROLLED TRIAL OF MEMANTINE AS AN ADJUNCT TO INJECTABLE EXTENDEDRELEASE NALTREXONE FOR OPIOID DEPENDENCE

There is preclinical support for using NMDA receptor glutamatergic antagonists to aid in naltrexone-based treatment of opioid dependence. We hypothesized that adding memantine will improve efficacy of extended-release (XR) naltrexone to prevent relapse. In this double blind study opioid-dependent pa...

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Autors principals: Bisaga, Adam, Sullivan, Maria A., Glass, Andrew, Mishlen, Kaitlyn, Carpenter, Kenneth M., Mariani, John J, Levin, Frances R., Nunes, Edward V.
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4007510/
https://ncbi.nlm.nih.gov/pubmed/24560438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsat.2014.01.005
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