Mutant p62(P392L) Stimulation of Osteoclast Differentiation in Paget's Disease of Bone

Paget's disease of the bone (PDB) is an autosomal dominant trait with genetic heterogeneity, characterized by abnormal osteoclastogenesis. Sequestosome 1 (p62) is a scaffold protein that plays an important role in receptor activator of nuclear factor κB (RANK) signaling essential for osteoclast...

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Bibliographische Detailangaben
Hauptverfasser: Sundaram, Kumaran, Shanmugarajan, Srinivasan, Rao, D. Sudhaker, Reddy, Sakamuri V.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Endocrine Society 2011
Schlagworte:
General Endocrinology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3198995/
https://ncbi.nlm.nih.gov/pubmed/21878516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2011-1225
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