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NFAM1 signaling enhances osteoclast formation and bone resorption activity in Paget's disease of bone

Paget's disease of bone (PDB) is marked by the focal activity of abnormal osteoclasts (OCLs)with excess bone resorption. We previously detected measles virus nucleocapsid protein (MVNP) transcripts in OCLs from patients with PDB. Also, MVNP stimulates pagetic OCL formation in vitro and in vivo....

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Detalhes bibliográficos
Publicado no:Bone
Main Authors: Sambandam, Yuvaraj, Sundaram, Kumaran, Saigusa, Takamitsu, Balasubramanian, Sundaravadivel, Reddy, Sakamuri V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5585872/
https://ncbi.nlm.nih.gov/pubmed/28506889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2017.05.013
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