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Microgravity Induction of TRAIL Expression in Preosteoclast Cells Enhances Osteoclast Differentiation

Evidence indicates that astronauts experience significant bone loss in space. We previously showed that simulated microgravity (μXg) using the NASA developed rotary cell culture system (RCCS) enhanced bone resorbing osteoclast (OCL) differentiation. However, the mechanism by which μXg increases OCL...

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Detalhes bibliográficos
Publicado no:Sci Rep
Principais autores: Sambandam, Yuvaraj, Baird, Kelsey L., Stroebel, Maxwell, Kowal, Emily, Balasubramanian, Sundaravadivel, Reddy, Sakamuri V.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4855152/
https://ncbi.nlm.nih.gov/pubmed/27142480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep25143
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