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Microgravity Induction of TRAIL Expression in Preosteoclast Cells Enhances Osteoclast Differentiation

Evidence indicates that astronauts experience significant bone loss in space. We previously showed that simulated microgravity (μXg) using the NASA developed rotary cell culture system (RCCS) enhanced bone resorbing osteoclast (OCL) differentiation. However, the mechanism by which μXg increases OCL...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Sambandam, Yuvaraj, Baird, Kelsey L., Stroebel, Maxwell, Kowal, Emily, Balasubramanian, Sundaravadivel, Reddy, Sakamuri V.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4855152/
https://ncbi.nlm.nih.gov/pubmed/27142480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep25143
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