Adenovirus-mediated siRNA targeting Bcl-xL inhibits proliferation, reduces invasion and enhances radiosensitivity of human colorectal cancer cells

INTRODUCTION: Bcl-xL, an important member of anti-apoptotic Bcl-2 family, plays critical roles in tumor progression and development. Previously, we have reported that overexpression of Bcl-xL was correlated with prognosis of colorectal cancer (CRC) patients. The aim of this study was to investigate...

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Detaylı Bibliyografya
Asıl Yazarlar: Yang, Jinsong, Sun, Ming, Zhang, Aiping, Lv, Chengyu, De, Wei, Wang, Zhaoxia
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2011
Konular:
Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3198948/
https://ncbi.nlm.nih.gov/pubmed/21970601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1477-7819-9-117
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