TTA-P2 Is a Potent and Selective Blocker of T-Type Calcium Channels in Rat Sensory Neurons and a Novel Antinociceptive Agent

Several agents that are preferential T-type calcium (T-channel) blockers have shown promise as being effective in alleviating acute and chronic pain, suggesting an urgent need to identify even more selective and potent T-channel antagonists. We used small, acutely dissociated dorsal root ganglion (D...

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Main Authors: Choe, WonJoo, Messinger, Richard B., Leach, Emily, Eckle, Veit-Simon, Obradovic, Aleksandar, Salajegheh, Reza, Jevtovic-Todorovic, Vesna, Todorovic, Slobodan M.
Formato: Artigo
Idioma:Inglês
Publicado: The American Society for Pharmacology and Experimental Therapeutics 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3198916/
https://ncbi.nlm.nih.gov/pubmed/21821734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.111.073205
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