Anti-gp120 Minibody Gene Transfer to Female Genital Epithelial Cells Protects against HIV-1 Virus Challenge In Vitro

BACKGROUND: Although cervico-vaginal epithelial cells of the female lower genital tract provide the initial defense system against HIV-1 infection, the protection is sometimes incomplete. Thus, enhancing anti-HIV-1 humoral immunity at the mucosal cell surface by local expression of anti-HIV-1 broadl...

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Detalhes bibliográficos
Main Authors: Abdel-Motal, Ussama M., Sarkis, Phuong T. N., Han, Thomas, Pudney, Jeffery, Anderson, Deborah J., Zhu, Quan, Marasco, Wayne A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3198777/
https://ncbi.nlm.nih.gov/pubmed/22031835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0026473
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