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Induction of a Protective Response in Mice by the Dengue Virus NS3 Protein Using DNA Vaccines

The dengue non-structural 3 (NS3) is a multifunctional protein, containing a serino-protease domain, located at the N-terminal portion, and helicase, NTPase and RTPase domains present in the C-terminal region. This protein is considered the main target for CD4+ and CD8+ T cell responses during dengu...

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Detalhes bibliográficos
Main Authors: Costa, Simone M., Yorio, Anna Paula, Gonçalves, Antônio J. S., Vidale, Mariana M., Costa, Emmerson C. B., Mohana-Borges, Ronaldo, Motta, Marcia A., Freire, Marcos S., Alves, Ada M. B.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3198735/
https://ncbi.nlm.nih.gov/pubmed/22031819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0025685
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