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The Synergistic Effect of Combined Immunization with a DNA Vaccine and Chimeric Yellow Fever/Dengue Virus Leads to Strong Protection against Dengue

The dengue envelope glycoprotein (E) is the major component of virion surface and its ectodomain is composed of domains I, II and III. This protein is the main target for the development of a dengue vaccine with induction of neutralizing antibodies. In the present work, we tested two different vacci...

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Bibliografske podrobnosti
Main Authors: Azevedo, Adriana S., Gonçalves, Antônio J. S., Archer, Marcia, Freire, Marcos S., Galler, Ricardo, Alves, Ada M. B.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3589436/
https://ncbi.nlm.nih.gov/pubmed/23472186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0058357
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