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DNA Vaccines against Dengue Virus Type 2 Based on Truncate Envelope Protein or Its Domain III

Two DNA vaccines were constructed encoding the ectodomain (domains I, II and III) of the DENV2 envelope protein (pE1D2) or only its domain III (pE2D2), fused to the human tissue plasminogen activator signal peptide (t-PA). The expression and secretion of recombinant proteins was confirmed in vitro i...

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Hlavní autoři: Azevedo, Adriana S., Yamamura, Anna M. Y., Freire, Marcos S., Trindade, Gisela F., Bonaldo, Myrna, Galler, Ricardo, Alves, Ada M. B.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3136928/
https://ncbi.nlm.nih.gov/pubmed/21779317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0020528
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