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pH-Dependent Conformational Changes in the HCV NS3 Protein Modulate Its ATPase and Helicase Activities
The hepatitis C virus (HCV) infects 170 to 200 million people worldwide and is, therefore, a major health problem. The lack of efficient treatments that specifically target the viral proteins or RNA and its high chronicity rate make hepatitis C the cause of many deaths and hepatic transplants annual...
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| 出版年: | PLoS One |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Public Library of Science
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4281115/ https://ncbi.nlm.nih.gov/pubmed/25551442 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0115941 |
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