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pH-Dependent Conformational Changes in the HCV NS3 Protein Modulate Its ATPase and Helicase Activities
The hepatitis C virus (HCV) infects 170 to 200 million people worldwide and is, therefore, a major health problem. The lack of efficient treatments that specifically target the viral proteins or RNA and its high chronicity rate make hepatitis C the cause of many deaths and hepatic transplants annual...
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| Yayımlandı: | PLoS One |
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| Asıl Yazarlar: | , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Public Library of Science
2014
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4281115/ https://ncbi.nlm.nih.gov/pubmed/25551442 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0115941 |
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