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The Xist RNA A-repeat comprises a novel AUCG tetraloop fold and a platform for multimerization

X-chromosome inactivation (XCI) in female mammals depends on the noncoding RNA X inactivation specific transcript (Xist). The mechanism of chromosome-wide silencing by Xist is poorly understood. While it is established that the 5′ region of Xist RNA, comprising the A-repeats and holding 7.5–8.5 copi...

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Detalhes bibliográficos
Main Authors: Duszczyk, Malgorzata M., Wutz, Anton, Rybin, Vladimir, Sattler, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3198591/
https://ncbi.nlm.nih.gov/pubmed/21947263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2747411
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