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The Xist RNA A-repeat comprises a novel AUCG tetraloop fold and a platform for multimerization
X-chromosome inactivation (XCI) in female mammals depends on the noncoding RNA X inactivation specific transcript (Xist). The mechanism of chromosome-wide silencing by Xist is poorly understood. While it is established that the 5′ region of Xist RNA, comprising the A-repeats and holding 7.5–8.5 copi...
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Huvudupphovsmän: | , , , |
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Materialtyp: | Artigo |
Språk: | Inglês |
Publicerad: |
Cold Spring Harbor Laboratory Press
2011
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Ämnen: | |
Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3198591/ https://ncbi.nlm.nih.gov/pubmed/21947263 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2747411 |
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