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Mapping the Universe of RNA Tetraloop Folds

We report a map of RNA tetraloop conformations constructed by calculating pairwise distances among all experimentally determined four-nucleotide hairpin loops. Tetraloops with similar structures are clustered together and, as expected, the two largest clusters are the canonical GNRA and UNCG folds....

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Detalles Bibliográficos
Publicado en:Biophys J
Main Authors: Bottaro, Sandro, Lindorff-Larsen, Kresten
Formato: Artigo
Idioma:Inglês
Publicado: The Biophysical Society 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5529312/
https://ncbi.nlm.nih.gov/pubmed/28673616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2017.06.011
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