SpliceTrap: a method to quantify alternative splicing under single cellular conditions

Motivation: Alternative splicing (AS) is a pre-mRNA maturation process leading to the expression of multiple mRNA variants from the same primary transcript. More than 90% of human genes are expressed via AS. Therefore, quantifying the inclusion level of every exon is crucial for generating accurate...

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Main Authors: Wu, Jie, Akerman, Martin, Sun, Shuying, McCombie, W. Richard, Krainer, Adrian R., Zhang, Michael Q.
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2011
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Original Papers
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3198574/
https://ncbi.nlm.nih.gov/pubmed/21896509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btr508
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