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Cellular prion protein conformation and function

In the otherwise highly conserved NMR structures of cellular prion proteins (PrP(C)) from different mammals, species variations in a surface epitope that includes a loop linking a β-strand, β2, with a helix, α2, are associated with NMR manifestations of a dynamic equilibrium between locally differen...

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Detalles Bibliográficos
Autores principales: Damberger, Fred F., Christen, Barbara, Pérez, Daniel R., Hornemann, Simone, Wüthrich, Kurt
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3198368/
https://ncbi.nlm.nih.gov/pubmed/21987789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1106325108
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