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Prion Protein-Detergent Micelle Interactions Studied by NMR in Solution

Cellular prion proteins, PrP(C), carrying the amino acid substitutions P102L, P105L, or A117V, which confer increased susceptibility to human transmissible spongiform encephalopathies, are known to form structures that include transmembrane polypeptide segments. Herein, we investigated the interacti...

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Detalhes bibliográficos
Main Authors: Hornemann, Simone, von Schroetter, Christine, Damberger, Fred F., Wüthrich, Kurt
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2755680/
https://ncbi.nlm.nih.gov/pubmed/19546219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.000430
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