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Prion Protein-Detergent Micelle Interactions Studied by NMR in Solution

Cellular prion proteins, PrP(C), carrying the amino acid substitutions P102L, P105L, or A117V, which confer increased susceptibility to human transmissible spongiform encephalopathies, are known to form structures that include transmembrane polypeptide segments. Herein, we investigated the interacti...

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Autores principales: Hornemann, Simone, von Schroetter, Christine, Damberger, Fred F., Wüthrich, Kurt
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2755680/
https://ncbi.nlm.nih.gov/pubmed/19546219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.000430
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