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NMR solution structure of the human prion protein

The NMR structures of the recombinant human prion protein, hPrP(23–230), and two C-terminal fragments, hPrP(90–230) and hPrP(121–230), include a globular domain extending from residues 125–228, for which a detailed structure was obtained, and an N-terminal flexibly disordered “tail.” The globular do...

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Detalhes bibliográficos
Main Authors: Zahn, Ralph, Liu, Aizhuo, Lührs, Thorsten, Riek, Roland, von Schroetter, Christine, López García, Francisco, Billeter, Martin, Calzolai, Luigi, Wider, Gerhard, Wüthrich, Kurt
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC26630/
https://ncbi.nlm.nih.gov/pubmed/10618385
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