Mitochondrial antiviral signaling protein (MAVS) monitors commensal bacteria and induces an immune response that prevents experimental colitis

RIG-I–like receptors (RLRs) activate host innate immune responses against virus infection through recruiting the mitochondrial adaptor protein MAVS (also known as IPS1, VISA, or CARDIF). Here we show that MAVS also plays a pivotal role in maintaining intestinal homeostasis. We found that MAVS knocko...

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Bibliografische gegevens
Hoofdauteurs: Li, Xiao-Dong, Chiu, Yu-Hsin, Ismail, Anisa S., Behrendt, Cassie L., Wight-Carter, Mary, Hooper, Lora V., Chen, Zhijian J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2011
Onderwerpen:
Biological Sciences
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3198352/
https://ncbi.nlm.nih.gov/pubmed/21960441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1107114108
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