Mitochondrial antiviral signaling protein (MAVS) monitors commensal bacteria and induces an immune response that prevents experimental colitis

RIG-I–like receptors (RLRs) activate host innate immune responses against virus infection through recruiting the mitochondrial adaptor protein MAVS (also known as IPS1, VISA, or CARDIF). Here we show that MAVS also plays a pivotal role in maintaining intestinal homeostasis. We found that MAVS knocko...

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Detalhes bibliográficos
Main Authors: Li, Xiao-Dong, Chiu, Yu-Hsin, Ismail, Anisa S., Behrendt, Cassie L., Wight-Carter, Mary, Hooper, Lora V., Chen, Zhijian J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3198352/
https://ncbi.nlm.nih.gov/pubmed/21960441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1107114108
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