Mitochondrial antiviral signaling protein (MAVS) monitors commensal bacteria and induces an immune response that prevents experimental colitis

RIG-I–like receptors (RLRs) activate host innate immune responses against virus infection through recruiting the mitochondrial adaptor protein MAVS (also known as IPS1, VISA, or CARDIF). Here we show that MAVS also plays a pivotal role in maintaining intestinal homeostasis. We found that MAVS knocko...

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Autori principali: Li, Xiao-Dong, Chiu, Yu-Hsin, Ismail, Anisa S., Behrendt, Cassie L., Wight-Carter, Mary, Hooper, Lora V., Chen, Zhijian J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2011
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3198352/
https://ncbi.nlm.nih.gov/pubmed/21960441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1107114108
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