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Crystal structure of the octameric pore of staphylococcal γ-hemolysin reveals the β-barrel pore formation mechanism by two components

Staphylococcal γ-hemolysin is a bicomponent pore-forming toxin composed of LukF and Hlg2. These proteins are expressed as water-soluble monomers and then assemble into the oligomeric pore form on the target cell. Here, we report the crystal structure of the octameric pore form of γ-hemolysin at 2.5 ...

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Bibliographische Detailangaben
Hauptverfasser: Yamashita, Keitaro, Kawai, Yuka, Tanaka, Yoshikazu, Hirano, Nagisa, Kaneko, Jun, Tomita, Noriko, Ohta, Makoto, Kamio, Yoshiyuki, Yao, Min, Tanaka, Isao
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3198349/
https://ncbi.nlm.nih.gov/pubmed/21969538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1110402108
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