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Subunit composition of a bicomponent toxin: Staphylococcal leukocidin forms an octameric transmembrane pore

Staphylococcal leukocidin pores are formed by the obligatory interaction of two distinct polypeptides, one of class F and one of class S, making them unique in the family of β-barrel pore-forming toxins (β-PFTs). By contrast, other β-PFTs form homo-oligomeric pores; for example, the staphylococcal α...

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Bibliographic Details
Main Authors: Miles, George, Movileanu, Liviu, Bayley, Hagan
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2002
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2373538/
https://ncbi.nlm.nih.gov/pubmed/11910032
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