Transmembrane β-barrel of staphylococcal α-toxin forms in sensitive but not in resistant cells

Staphylococcal α-toxin is a 293-residue, single-chain polypeptide that spontaneously assembles into a heptameric pore in target cell membranes. To identify the pore-forming domain, substitution mutants have been produced in which single cysteine residues were introduced throughout the toxin molecule...

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Detalles Bibliográficos

Publicado en:	Proc Natl Acad Sci U S A
Principais autores:	Valeva, Angela, Walev, Iwan, Pinkernell, Matthias, Walker, Barbara, Bayley, Hagan, Palmer, Michael, Bhakdi, Sucharit
Formato:	Artigo
Idioma:	Inglês
Publicado:	National Academy of Sciences 1997
Assuntos:	Biological Sciences
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC23553/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9326657/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.21.11607
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