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Taxol, a microtubule stabilizing agent, blocks the replication of Trypanosoma cruzi.

Taxol, an experimental antitumor agent and stabilizer of microtubules, inhibits in vitro replication of the human pathogenic hemoflagellate Trypanosoma cruzi. Micromolar concentrations of the drug prevent the completion of cell division in these organisms but allow the multiplication of cell organel...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Baum, S G, Wittner, M, Nadler, J P, Horwitz, S B, Dennis, J E, Schiff, P B, Tanowitz, H B
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 1981
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC319834/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6117077/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.78.7.4571
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