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Antagonism by taxol of effects of microtubule-disrupting agents on lymphocyte cAMP metabolism and cell function.

Several microtubule-disrupting agents (colchicine, demecolcine, vinblastine, vincristine, podophyllotoxin, and nocodazole) have been shown to inhibit lymphocyte-mediated cytolysis. These agents also enhanced the prostaglandin E1-induced rise in cAMP levels in these cytolytic lymphocytes. Taxol, a na...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Wolberg, G, Stopford, C R, Zimmerman, T P
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1984
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC345535/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6145157/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.81.11.3496
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