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Defective cAMP-dependent phosphorylation of intact T lymphocytes in active systemic lupus erythematosus.

The present study was undertaken to establish whether cAMP-dependent phosphorylation of endogenous substrates is impaired in T lymphocytes from subjects with active systemic lupus erythematosus (SLE). In normal human T lymphocytes, the cell-permeable cAMP analog, N6,O2'-dibutyryladenosine 3',5'-cycl...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Hasler, P, Schultz, L A, Kammer, G M
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1990
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC53608/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2155428/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.5.1978
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