Defective cAMP-dependent phosphorylation of intact T lymphocytes in active systemic lupus erythematosus.
The present study was undertaken to establish whether cAMP-dependent phosphorylation of endogenous substrates is impaired in T lymphocytes from subjects with active systemic lupus erythematosus (SLE). In normal human T lymphocytes, the cell-permeable cAMP analog, N6,O2'-dibutyryladenosine 3',5'-cycl...
Guardat en:
| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
1990
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC53608/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2155428/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.5.1978 |
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