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High-resolution imaging reveals indirect coordination of opposite motors and a role for LIS1 in high-load axonal transport

The specific physiological roles of dynein regulatory factors remain poorly understood as a result of their functional complexity and the interdependence of dynein and kinesin motor activities. We used a novel approach to overcome these challenges, combining acute in vivo inhibition with automated h...

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Main Authors: Yi, Julie Y., Ori-McKenney, Kassandra M., McKenney, Richard J., Vershinin, Michael, Gross, Steven P., Vallee, Richard B.
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3198168/
https://ncbi.nlm.nih.gov/pubmed/22006948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201104076
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