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Development of a Novel Ligand, [(11)C]TGN-020, for Aquaporin 4 Positron Emission Tomography Imaging

[Image: see text] Aquaporin 4 (AQP4), the most abundant isozyme of the water specific membrane transporter aquaporin family, has now been implicated to play a significant role in the pathogenesis of various disease processes of the nervous system from epilepsy to Alzheimer’s disease. Considering its...

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Autors principals: Nakamura, Yukihiro, Suzuki, Yuji, Tsujita, Mika, Huber, Vincent J., Yamada, Kenichi, Nakada, Tsutomu
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2011
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3198134/
https://ncbi.nlm.nih.gov/pubmed/22022637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn2000525
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