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Effects of an Aquaporin 4 Inhibitor, TGN-020, on Murine Diabetic Retina

Purpose: To investigate the effect of a selective aquaporin 4 (AQP4) inhibitor, 2-(nicotinamide)-1,3,4-thiadiazole (TGN-020), on the expression of vascular endothelial growth factor (VEGF) and reactive oxygen species (ROS) production, as well as on the retinal edema in diabetic retina. Methods: Intr...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Oosuka, Shou, Kida, Teruyo, Oku, Hidehiro, Horie, Taeko, Morishita, Seita, Fukumoto, Masanori, Sato, Takaki, Ikeda, Tsunehiko
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7177210/
https://ncbi.nlm.nih.gov/pubmed/32230876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21072324
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