Temperature-sensitive RNA polymerase mutants of a picornavirus.

Temperature-sensitive (ts) RNA polymerase mutants of a picornavirus are reported. Two foot-and-mouth disease virus (FMDV) mutants designated ts 22 and ts 115 have been characterized. As judged by isoelectric focusing, both have charge alterations in P56a, the FMDV RNA polymerase protein. Virus RNA s...

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Bibliographic Details
Main Authors: Lowe, P A, King, A M, McCahon, D, Brown, F, Newman, J W
Format: Artigo
Language:Inglês
Published: 1981
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC319808/
https://ncbi.nlm.nih.gov/pubmed/6270678
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