Temperature-sensitive RNA polymerase mutants of a picornavirus.

Temperature-sensitive (ts) RNA polymerase mutants of a picornavirus are reported. Two foot-and-mouth disease virus (FMDV) mutants designated ts 22 and ts 115 have been characterized. As judged by isoelectric focusing, both have charge alterations in P56a, the FMDV RNA polymerase protein. Virus RNA s...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Lowe, P A, King, A M, McCahon, D, Brown, F, Newman, J W
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1981
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC319808/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6270678/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.78.7.4448
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