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Mechanistic Studies of Antibody-Mediated Clearance of Tau Aggregates Using an ex vivo Brain Slice Model

Recent studies have shown that immunotherapy clears amyloid beta (Aβ) plaques and reduces Aβ levels in mouse models of Alzheimer’s disease (AD), as well as in AD patients. Tangle pathology is also relevant for the neurodegeneration in AD, and our studies have shown that active immunization with an A...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Krishnamurthy, Pavan K., Deng, Yan, Sigurdsson, Einar M.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Frontiers Research Foundation 2011
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3198029/
https://ncbi.nlm.nih.gov/pubmed/22025915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fpsyt.2011.00059
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