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Isolation of a taxol-resistant Chinese hamster ovary cell mutant that has an alteration in alpha-tubulin.
Taxol is a plant alkaloid that has antimitotic activity and appears to stabilize microtubules [Schiff, P. B., Fant, J. & Horwitz, S. B. (1979) Nature (London) 277, 665-667]. Taxol-resistant cells were selected from a population of UV-mutagen-treated Chinese hamster ovary cells by a single-step p...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
1981
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC319795/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6117076/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.78.7.4388 |
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