Isolation of a taxol-resistant Chinese hamster ovary cell mutant that has an alteration in alpha-tubulin.
Taxol is a plant alkaloid that has antimitotic activity and appears to stabilize microtubules [Schiff, P. B., Fant, J. & Horwitz, S. B. (1979) Nature (London) 277, 665-667]. Taxol-resistant cells were selected from a population of UV-mutagen-treated Chinese hamster ovary cells by a single-step proce...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
1981
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC319795/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6117076/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.78.7.4388 |
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