Llwytho...
Dominant-Negative Mechanism of Leukemogenic PAX5 Fusions
PAX5 encodes a master regulator of B-cell development. It fuses to other genes associated with acute lymphoblastoid leukemia (ALL). These fusion products are potent dominant-negative (DN) inhibitors of wild-type PAX5 resulting in a blockade of B-cell differentiation. Here, we show that multimerizati...
Wedi'i Gadw mewn:
| Prif Awduron: | , , , , |
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| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
2011
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3197879/ https://ncbi.nlm.nih.gov/pubmed/21765475 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2011.291 |
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