IRF8 Regulates Bax Transcription in vivo in Primary Myeloid Cells

A prominent phenotype of IRF8 knock out (IRF8 KO) mice is the uncontrolled expansion of immature myeloid cells. The molecular mechanism underlying this myeloproliferative syndrome is still elusive. In this study, we observed that Bax expression level is low in bone marrow (BM) preginitor cells and i...

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Hlavní autoři: Yang, Jine, Hu, Xiaolin, Zimmerman, Mary, Torres, Christina M., Yang, Dafeng, Smith, Sylvia B., Liu, Kebin
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3197864/
https://ncbi.nlm.nih.gov/pubmed/21949018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1101034
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