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IRF8 Regulates Bax Transcription in vivo in Primary Myeloid Cells

A prominent phenotype of IRF8 knock out (IRF8 KO) mice is the uncontrolled expansion of immature myeloid cells. The molecular mechanism underlying this myeloproliferative syndrome is still elusive. In this study, we observed that Bax expression level is low in bone marrow (BM) preginitor cells and i...

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Detalhes bibliográficos
Main Authors: Yang, Jine, Hu, Xiaolin, Zimmerman, Mary, Torres, Christina M., Yang, Dafeng, Smith, Sylvia B., Liu, Kebin
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3197864/
https://ncbi.nlm.nih.gov/pubmed/21949018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1101034
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