Effects of DAPT and Atoh1 Overexpression on Hair Cell Production and Hair Bundle Orientation in Cultured Organ of Corti from Neonatal Rats

BACKGROUND: In mammals, hair cells do not undergo spontaneous regeneration when they are damaged and result in permanent hearing loss. Previous studies in cultured Organ of Corti dissected from neonatal animals have shown that both DAPT (r-secretase inhibitor in the Notch signal pathway) treatment a...

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מידע ביבליוגרפי
Main Authors: Zhao, Li-Dong, Guo, Wei-Wei, Lin, Chang, Li, Li-Xian, Sun, Jian-He, Wu, Nan, Ren, Li-Li, Li, Xin-Xin, Liu, Hui-Zhan, Young, Wie-Yen, Gao, Wei-Qiang, Yang, Shi-Ming
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2011
נושאים:
Research Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3197578/
https://ncbi.nlm.nih.gov/pubmed/22028767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0023729
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