Opiates inhibit adenylate cyclase by stimulating GTP hydrolysis.
Specific, GTP hydrolysis catalyzed by membranes prepared from neuroblastoma--glioma (NG108-15) hybrid cells can be measured in the presence of adenosine-5'-[beta, gamma-imido] triphosphate (p[NH]ppA), ATP, and a nucleotide triphosphate-regenerating system. Opiates and opioid peptides stimulate low K...
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| Publicado en: | Proc Natl Acad Sci U S A |
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| Autores principales: | , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
1981
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC319753/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6117072/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.78.7.4185 |
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