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Opiates inhibit adenylate cyclase by stimulating GTP hydrolysis.

Specific, GTP hydrolysis catalyzed by membranes prepared from neuroblastoma--glioma (NG108-15) hybrid cells can be measured in the presence of adenosine-5'-[beta, gamma-imido] triphosphate (p[NH]ppA), ATP, and a nucleotide triphosphate-regenerating system. Opiates and opioid peptides stimulate low K...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Proc Natl Acad Sci U S A
Prif Awduron: Koski, G, Klee, W A
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 1981
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC319753/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6117072/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.78.7.4185
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