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Reduced expression of multiple forms of the alpha subunit of the stimulatory GTP-binding protein in pseudohypoparathyroidism type Ia.

We examined the expression of the alpha subunit of the stimulatory GTP-binding protein (Gs) in fibroblasts of subjects with pseudohypoparathyroidism (PHP) type Ia by transfer blot hybridization and S1 nuclease analyses. Six subjects with PHP type Ia showed decreased steady-state content of Gs alpha...

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Bibliographic Details
Main Authors: Carter, A, Bardin, C, Collins, R, Simons, C, Bray, P, Spiegel, A
Format: Artigo
Language:Inglês
Published: 1987
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC299273/
https://ncbi.nlm.nih.gov/pubmed/2890163
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