Endogenous Epoxygenases Are Modulators of Monocyte/Macrophage Activity

BACKGROUND: Arachidonic acid is metabolized through three major metabolic pathways, the cyclooxygenase, lipoxygenase and CYP450 enzyme systems. Unlike cyclooxygenase and lipoxygenases, the role of CYP450 epoxygenases in monocyte/macrophage-mediated responses is not known. METHODOLOGY/PRINCIPAL FINDI...

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Main Authors: Bystrom, Jonas, Wray, Jessica A., Sugden, Mary C., Holness, Mark J., Swales, Karen E., Warner, Timothy D., Edin, Matthew L., Zeldin, Darryl C., Gilroy, Derek W., Bishop-Bailey, David
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3197524/
https://ncbi.nlm.nih.gov/pubmed/22028915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0026591
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