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Isolation of Fidelity Variants of RNA Viruses and Characterization of Virus Mutation Frequency
RNA viruses use RNA dependent RNA polymerases to replicate their genomes. The intrinsically high error rate of these enzymes is a large contributor to the generation of extreme population diversity that facilitates virus adaptation and evolution. Increasing evidence shows that the intrinsic error ra...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
MyJove Corporation
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3197063/ https://ncbi.nlm.nih.gov/pubmed/21712796 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/2953 |
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