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A Strategy to Identify de Novo Mutations in Common Disorders such as Autism and Schizophrenia

There are several lines of evidence supporting the role of de novo mutations as a mechanism for common disorders, such as autism and schizophrenia. First, the de novo mutation rate in humans is relatively high, so new mutations are generated at a high frequency in the population. However, de novo mu...

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Detalhes bibliográficos
Main Authors: Julie, Gauthier, Hamdan, Fadi F., Rouleau, Guy A.
Formato: Artigo
Idioma:Inglês
Publicado em: MyJove Corporation 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3197027/
https://ncbi.nlm.nih.gov/pubmed/21712793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/2534
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