Rare mutations in N-methyl-D-aspartate glutamate receptors in autism spectrum disorders and schizophrenia

Pharmacological, genetic and expression studies implicate N-methyl-D-aspartate (NMDA) receptor hypofunction in schizophrenia (SCZ). Similarly, several lines of evidence suggest that autism spectrum disorders (ASD) could be due to an imbalance between excitatory and inhibitory neurotransmission. As p...

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Autores principales: Tarabeux, J, Kebir, O, Gauthier, J, Hamdan, F F, Xiong, L, Piton, A, Spiegelman, D, Henrion, É, Millet, B, Fathalli, F, Joober, R, Rapoport, J L, DeLisi, L E, Fombonne, É, Mottron, L, Forget-Dubois, N, Boivin, M, Michaud, J L, Drapeau, P, Lafrenière, R G, Rouleau, G A, Krebs, M-O
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2011
Materias:
Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3309470/
https://ncbi.nlm.nih.gov/pubmed/22833210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tp.2011.52
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